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  • Writer's pictureDr Edin Hamzić

Point Mutation


What is Point Mutation?

A point mutation is any change in the DNA or RNA sequence where a single nucleotide base is changed (substituted), inserted, or deleted. Point mutations do not involve detectable structural alterations such as loss or rearrangement of the chromosome.

What is the rate of point mutations?

The point mutation rate per locus in eukaryote organisms is about 1 in 100000 and may vary from locus to locus and among various organisms.

The point mutation rate per nucleotide of a locus is in the range of 1 in 100000000.


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